Tissue Lysates
Meso Scale Discovery Total S6RP Whole Cell Lysate
The Meso Scale Discovery S6RP is a 96-well plate coated with streptavidin for use in multiplex immunoassays It has high binding capacity and low non-specific binding The plate is compatible with MSD s electrochemiluminescence detection technology for sensitive and rapid quantification of biomarkers With its high-sensitivity and broad dynamic range the S6RP plate enables simultaneous detection of up to 10 biomarkers per well from a variety of sample types including serum plasma and cell culture supernatants The plate is suitable for sandwich immunoassays using MSD SULFO-TAG labels
Cayman Chemical CarbaprostacyclIn 100ug
Carbaprostacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. This implies rapid metabolic inactivation of carbaprostacyclin.{509} Carbaprostacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2.{509,513} The ED50 of carbaprostacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM.{511} It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 µM.{4061}
Biochain Institute Inc Universal Protein Lysate: Rat Normal Tissues, 2x0.5 mg/PK
BioChain's Universal Protein Lysate is the total protein isolated from a variety of tissue sources including human, monkey, dog, mouse, and rat, to ensure the broadest coverage of proteins. It can be used as controls for comparison of protein expression and for antibody microarray study. Our product is manufactured on an industrial scale to minimize lot-to-lot variation.
Cayman Chemical Sartrypyron D 100ug
A fungal metabolite; inhibits NFRD (IC50 = 1.7 µM in A. suum mitochondria) and NADH oxidase (IC50 = 3 µM in bovine heart mitochondria); active against B. subtilis, K. rhizophila, and M. smegmatis in disc assays
Cayman Chemical 16 17-DIHDPA 100ug
A DHA metabolite that inhibits VEGF-induced angiogenesis and reduces cancer cell metastasis in mice
Abcam Lectin Array 70.
Lectin Array 70.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical BRD4 bromodomaIn 1humnre 100ug
Source: Recombinant human N-terminal GST-tagged BRD4 bromodomain 1 expressed in E. coli • Amino acids: 49-170 • MW: 41.4 kDa
Cayman Chemical 27-alkyn Cholesterol 100ug
An alkyne derivative of cholesterol for click chemistry; has been used to track cholesterol metabolism and localization
Cayman Chemical KazusamycIn B 100ug
A bacterial metabolite; has antifungal activity against S. pombe and R. javanicus (MICs = 0.05 and 2.13 UG/ml, respectively); halts the cell cycle at the G1 phase and induces nuclear condensation in L1210 cells at 5 ng/ml; inhibits nuclear-to-cytosolic transport of Rev in HeLa cells expressing Rev (IC50 = 6.3 nM); cytotoxic to L1210 and HCT-8 cells (IC50 = 1.8 and 1.6 ng/ml, respectively); reduces tumor growth in a variety of murine tumor and mouse xenograft models
Cayman Chemical 11S 12R-EET 100UG
An oxylipin and a metabolite of arachidonic acid; activates KCa1.1/BK in isolated rat coronary small arterial smooth muscle cells at 50 nM; induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 20 pM) and denuded porcine subepicardial arterioles (EC50 = 10 pM)
Cayman Chemical 5-IPF2a-VI 100ug
A potent inhibitor of both human and mouse soluble epoxide hydrolase (IC50 3.7 and 2.8 nM respectively) has superior pharmacokinetics compared to the 1-adamantylurea based inhibitors like AUDA
Sino Biological Recombinant Human CNR1 Protein (VLP, Flag-Strep & His tag)
A DNA sequence encoding the Human CNR1 (P21554-1) (Met1-Ser414) was expressed, with a Flag tag followed by a Strep Tag at the N-terminus, a polyhistidine tag at the C-terminus. This protein was prepared using our VLP platform.As an innovative technology platform, VLPs are generated through the self-assembly of viral proteins in HEK293 cells. This process efficiently integrates membrane proteins onto the VLP surface, preserving their native conformation and yielding soluble, high-concentration proteins that are ideally suited for immunization and antibody screening.
Cayman Chemical 15deoxy12 14ProstaglndIn 100ug
A metabolite of PGD2 formed by the elimination of two molecules of water; binds to PPARγ with an EC50 value of 2 µM